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Study: Both Oxford and Pfizer vaccines are effective against the Brazilian version of Corona



A study conducted by the University of Oxford revealed that its vaccine and the vaccine made by Pfizer work well against the P.1 strain that first appeared in Manaus, Brazil, and it also works against the Kent variant, which is the English version of the virus, as the vaccines have proven to be very effective against the dominant Kent strain. In the United Kingdom, which reduces deaths and hospital rates by more than 85%.


According to the British newspaper "Daily Mail" report, scientists initially feared that the Brazilian alternative would be resistant to vaccines because it contains a number of worrisome mutations, in addition to those it shares with the Kent strain, so far there have been 12 cases of the Brazilian type in the United Kingdom 9 in England and 3 in Scotland All patients had direct or indirect travel links to Brazil.


The study revealed from blood samples taken from people who were vaccinated for various types of corona and monitored their antibody responses, that the vaccines produced approximately three times fewer antibodies against the Kent and Brazil variants compared to the original strain, and the researchers said that this is more than enough to neutralize the viruses, as they stimulated Vaccines are up to 9 times less antibody when exposed to the South African variant, which has been detected in hundreds of people in the UK.


But antibodies are not the only part of the immune response to Coronavirus, white blood cells also play an important role, which means that even if vaccines do not produce a strong antibody response, they still have to prevent severe disease.


Vaccine makers said earlier that vaccines will still prevent the vast majority of people from contracting this strain, and they say that in a small number of people who have been vaccinated and who are still infected with it, their symptoms will decrease to a cold, which means that very simple symptoms appear on them.


Professor Gavin Scratchon, the medical expert who led the research, said: "This study broadens our understanding of the role of changes in spike protein in escaping the human immune response, which is measured as equivalent to antibody levels."


The study used blood samples from people who had natural antibodies resulting from infection with the Corona virus and from those whose antibodies were stimulated by the Oxford or Pfizer vaccine, and found a nearly three-fold decrease in the level of virus neutralization by the antibodies produced by the Oxford and Pfizer vaccine for the Kent and Brazil variants. When compared to the original breed.


The university said that these data indicate that the natural antibodies caused by the vaccine are still able to neutralize these variables, but at lower levels. Most importantly, the "Brazilian" P1 strain may be less resistant to these antibodies than was initially feared.

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